Endocrine Abstracts

Introduction: Heart failure (HF) morbidity and mortality are increasing at an alarming rate in people with type 2 diabetes (T2D). Myocardial dysfunction may develop without ischemic heart disease (IHD), hypertension, or valvular pathologies, and which is defined as diabetic cardiomyopathy (DCM). Although the pathophysiology of DCM is unclear, DCM is initially characterised by myocardial fibrosis, dysfunctional remodelling, and associated diastolic dysfunction, later by systoli...

Introduction: Global mean surface air temperatures have risen by about 1 °C in the past century and are projected to increase by another 1–6 °C by 2100 depending on greenhouse gas emissions. As a result of the increase in mean temperatures, heatwaves have become more severe, frequent, and prevalent. Heat exposure in ambient temperature is associated with all-cause diabetes mortality and all-cause hospitalisation in people with diabetes. However, there is a pauci...